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Gene Expression Data
Assay Details
Assay
Reference: J:35305 Bogue CW, et al., Expression of Hoxb genes in the developing mouse foregut and lung. Am J Respir Cell Mol Biol. 1996 Aug;15(2):163-71
Assay type: RNA in situ
MGI Accession ID: MGI:5484882
Gene symbol: Hoxb4
Gene name: homeobox B4
Probe: Hoxb4 cDNA3
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 1: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: foregut Present Regionally restricted 1A b4 Anterior boundary is the fourth branchial arch. Higher levels at the level of the lung buds and caudally.
TS15: midgut Present Regionally restricted 1A b4 Expression extends caudially to the region from which the liver develops.

Specimen 2: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: lung mesenchyme Present Uniform 2_E10.5 b4
TS17: main bronchus mesenchyme Present Uniform 2_E10.5 b4
TS17: trachea mesenchyme Present Uniform 2_E10.5 b4
TS17: lung epithelium Absent 2_E10.5 b4
TS17: main bronchus epithelium Absent 2_E10.5 b4
TS17: trachea epithelium Absent 2_E10.5 b4

Specimen 2: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: lung mesenchyme Present Uniform 2_E11.5 b4
TS19: main bronchus mesenchyme Present Uniform 2_E11.5 b4
TS19: trachea mesenchyme Present Uniform 2_E11.5 b4
TS19: lung epithelium Absent 2_E11.5 b4
TS19: main bronchus epithelium Absent 2_E11.5 b4
TS19: trachea epithelium Absent 2_E11.5 b4

Specimen 2: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: carina trachea mesenchyme Strong 2_E12.5 b4
TS20: trachea Present 2_E12.5 b4

Specimen 3: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: lung mesenchyme Present 3
TS19: lung epithelium Absent 3

Specimen not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: lung mesenchyme Present
TS22: lung epithelium Absent


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
09/24/2024
MGI 6.24
The Jackson Laboratory