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Gene Expression Data
Assay Details
Assay
Reference: J:77820 Kameda Y, et al., Homeobox gene hoxa3 is essential for the formation of the carotid body in the mouse embryos. Dev Biol. 2002 Jul 1;247(1):197-209
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5506903
Gene symbol: Uchl1
Gene name: ubiquitin carboxy-terminal hydrolase L1
Antibody: anti-PGP 9.5
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 2A: embryonic day 16.5 (more )
Structure Level Pattern Image Note
TS24: carotid artery Present 2A Expressed in the glomus cells of the carotid body.
TS24: superior cervical ganglion Present 2A

Specimen 3C: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: superior cervical ganglion Strong 3C Expressed in the neurons.
TS26: carotid body Present 3C Expressed in the glomus cells and nerve fibers within the carotid body parenchyma.

Specimen 5A: embryonic day 13.0 (more )
Structure Level Pattern Image Note
TS21: common carotid artery Present Regionally restricted 5A Expressed in the carotid body rudiment as aggregations of cells in the medial wall.
TS21: glossopharyngeal nerve Present 5A
TS21: vagus ganglion Present 5A
TS21: superior cervical ganglion Present 5A Also expressed in some neurons encountered around the carotid body rudiment, which were continuous with the superior cervical ganglion.

Specimen 5C: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: internal carotid artery Present Regionally restricted 5C Faintly expressed in the carotid body rudiment as aggregations of cells in the ventromedial wall. Also expressed in the nerve fascicules and neurons derived from the superior cervical ganglion.
TS21: glossopharyngeal nerve Present 5C
TS21: superior cervical ganglion Present 5C
TS21: vagus ganglion Present 5C

Specimen 5E: embryonic day 13.5; Hoxa3tm1Mrc/Hoxa3tm1Mrc (more )
Structure Level Pattern Image Note
TS21: internal carotid artery Present Regionally restricted 5E Expressed in the nerve fascicules and neurons derived from the superior cervical ganglion. No carotid body rudiment was formed in the wall.
TS21: glossopharyngeal nerve Present 5E
TS21: superior cervical ganglion Present 5E
TS21: vagus ganglion Present 5E

Specimen not shown: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: common carotid artery Strong Regionally restricted Expressed in the carotid body.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/12/2024
MGI 6.24
The Jackson Laboratory