Uchl1 Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:171409 GUDMAP Consortium, GUDMAP: the GenitoUrinary Development Molecular Anatomy Project. www.gudmap.org. 2004;
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:5548313
Gene symbol:	Uchl1
Gene name:	ubiquitin carboxy-terminal hydrolase L1

Antibody:	anti-PGP 9.5 (CL95101)
Detection system:	Secondary antibody coupled to Alexa Fluor 594

Results

GUDMAP:20871 ©

Specimen GUDMAP:20871: embryonic day 12.5 (more

)
Note: Double labeled: red = Uchl1 (PGP9.5); green = Th

Structure	Level	Pattern	Image	Note
TS20: urothelium of primitive bladder	Present		GUDMAP:20871

GUDMAP:20873 ©

Specimen GUDMAP:20873: embryonic day 14.5 (more

)
Note: Double labeled: red = Uchl1 (PGP9.5); green = Acta2 (alpha smooth muscle actin)

Structure	Level	Pattern	Image	Note
TS22: pelvic ganglion	Present		GUDMAP:20873
TS22: urothelium of bladder	Present	Graded	GUDMAP:20873	Stronger expression in more superficial epithelial cells.
TS22: nerve of bladder	Present		GUDMAP:20873
TS22: nerve of lamina propria of bladder	Present		GUDMAP:20873
TS22: nerve of detrusor muscle of bladder	Present	Graded	GUDMAP:20873	dorsal expression
TS22: nerve of outer layer of bladder	Present	Graded	GUDMAP:20873	dorsal expression
TS22: nerve of urothelium of bladder	Absent		GUDMAP:20873

GUDMAP:20909 ©

Specimen GUDMAP:20909: embryonic day 18.5 (more

)
Note: Double labeled: red = Uchl1 (PGP9.5); green = Th

Structure	Level	Pattern	Image	Note
TS26: nerve of bladder	Present		GUDMAP:20909	Adjacent to blood vessel
TS26: pelvic ganglion	Present		GUDMAP:20909
TS26: urothelium of bladder	Present	Regionally restricted	GUDMAP:20909	Stronger expression in more superficial epithelial cells.
TS26: nerve of pelvic urethra of male	Present		GUDMAP:20909
TS26: nerve of ureter	Present		GUDMAP:20909
TS26: nerve of urothelium of bladder	Present		GUDMAP:20909
TS26: nerve of lamina propria of bladder	Present		GUDMAP:20909
TS26: nerve of detrusor muscle of bladder	Present		GUDMAP:20909
TS26: nerve of outer layer of bladder	Present		GUDMAP:20909

GUDMAP:21015 ©

Specimen GUDMAP:21015: embryonic day 13.5 (more

)

Structure	Level	Pattern	Image	Note
TS21: primitive bladder	Present	Graded	GUDMAP:21015	dorsal expression; Axons only associated with the dorsal aspect of the bladder. They comprise large bundles of axons on/near the outer edge of the detrusor, with a small number of axons penetrating the detrusor. None were detected in the lamina propria or associated with the urothelium.
TS21: nerve of primitive bladder	Present	Graded	GUDMAP:21015	dorsal expression; Axons only associated with the dorsal aspect of the bladder. They comprise large bundles of axons on/near the outer edge of the detrusor, with a small number of axons penetrating the detrusor. None were detected in the lamina propria or associated with the urothelium.

GUDMAP:21195 ©

Specimen GUDMAP:21195: postnatal day 21 (more

)
Note: Double labeled: red = Uchl1 (PGP9.5); green = Th

Structure	Level	Pattern	Image	Note
TS28: nerve of prostate gland	Present		GUDMAP:21195
TS28: pelvic ganglion	Present		GUDMAP:21195
TS28: nerve of bladder	Present		GUDMAP:21195
TS28: urothelium of bladder	Present	Regionally restricted	GUDMAP:21195	Stronger expression in more superficial epithelial cells.
TS28: nerve of urothelium of bladder	Present		GUDMAP:21195
TS28: nerve of lamina propria of bladder	Present		GUDMAP:21195
TS28: nerve of detrusor muscle of bladder	Present		GUDMAP:21195
TS28: nerve of outer layer of bladder	Present		GUDMAP:21195

GUDMAP:21283 ©

Specimen GUDMAP:21283: postnatal day 7 (more

)
Note: Double labeled: red = Uchl1 (PGP9.5); green = Th

Structure	Level	Pattern	Image	Note
TS28: pelvic ganglion	Present		GUDMAP:21283
TS28: nerve of pelvic urethra of female	Present		GUDMAP:21283
TS28: nerve of bladder	Present		GUDMAP:21283
TS28: urothelium of bladder	Present	Regionally restricted	GUDMAP:21283	Slightly higher expression in superficial urothelial cells
TS28: nerve of urothelium of bladder	Present		GUDMAP:21283
TS28: nerve of lamina propria of bladder	Present		GUDMAP:21283
TS28: nerve of detrusor muscle of bladder	Present		GUDMAP:21283
TS28: nerve of outer layer of bladder	Present		GUDMAP:21283

GUDMAP:21397 ©

Specimen GUDMAP:21397: postnatal day 21 (more

)
Note: Double labeled: red = Uchl1 (PGP9.5); green = Th

Structure	Level	Pattern	Image	Note
TS28: nerve of bladder	Present		GUDMAP:21397
TS28: urothelium of bladder	Present	Regionally restricted	GUDMAP:21397	Stronger expression in more superficial urothelial cells
TS28: nerve of urothelium of bladder	Present		GUDMAP:21397
TS28: nerve of lamina propria of bladder	Present		GUDMAP:21397
TS28: nerve of detrusor muscle of bladder	Present		GUDMAP:21397
TS28: nerve of outer layer of bladder	Present		GUDMAP:21397

GUDMAP:21372 ©

Specimen GUDMAP:21372: embryonic day 14.5; Chat^tm1(cre)Lowl/Chat⁺, Gt(ROSA)26Sor^tm1(EYFP)Cos/Gt(ROSA)26Sor⁺ (more

)
Note: Conditional mutant.

Structure	Level	Pattern	Image	Note
TS22: nerve of bladder	Present		GUDMAP:21372
TS22: urothelium of bladder	Present		GUDMAP:21372	Although this is considered a pan-neuronal marker, urothelial labelling is consistently seen.
TS22: genital tubercle of male	Present		GUDMAP:21372
TS22: pelvic ganglion	Present		GUDMAP:21372
TS22: nerve of detrusor muscle of bladder	Present	Graded	GUDMAP:21372
TS22: nerve of outer layer of bladder	Present	Graded	GUDMAP:21372
TS22: nerve of genital tubercle of male	Present		GUDMAP:21372
TS22: nerve of lamina propria of bladder	Present	Graded	GUDMAP:21372

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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