Gene Expression Data
Assay Details
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Assay
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Reference:
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J:170558
Hoeing K, et al., Presenilin-1 processing of ErbB4 in fetal type II cells is necessary for control of fetal lung maturation. Biochim Biophys Acta. 2011 Mar;1813(3):480-91
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:5644474
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Gene symbol:
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Psen1
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Gene name:
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presenilin 1
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Antibody:
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anti-PSEN-1
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Detection system:
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Biotinylated secondary antibody/[Strept]avidin coupled to alkaline phosphatase
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Results
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Specimen
1B:
embryonic day 16.0
(more  )
Specimen
1B:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 16.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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Specimen
1C:
embryonic day 17.0
(more )
Specimen
1C:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 17.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS25: lung epithelium |
Present |
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1C
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Incresed expression compared with that of E16.
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| TS25: bronchiole epithelium |
Present |
Regionally restricted |
1C
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Expressed in the epithelium at the transition from distal bronchioles to alveolar ducts.
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| TS25: lung mesenchyme |
Strong |
Regionally restricted |
1C
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Expressed in mesenchymal cells adjacent to cuboidal epithelium, but clusters of mesenchymal cells between the airways were less positive.
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Specimen
1D:
embryonic day 18.0
(more )
Specimen
1D:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 18.0
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Age Note:
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Age of embryo at noon of plug day not specified in reference.
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Cryosection
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: lung epithelium |
Present |
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1D
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Incresed expression compared with that of E16.
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| TS26: lung mesenchyme |
Strong |
Regionally restricted |
1D
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Expressed in mesenchymal cells adjacent to cuboidal epithelium, but clusters of mesenchymal cells between the airways were less positive.
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| TS26: bronchiole epithelium |
Present |
Regionally restricted |
1D
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Expressed in the epithelium at the transition from distal bronchioles to alveolar ducts.
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Analysis Tools