About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:57476 Marine JC, et al., SOCS3 is essential in the regulation of fetal liver erythropoiesis. Cell. 1999 Sep 3;98(5):617-27
Assay type: Immunohistochemistry
MGI Accession ID: MGI:5707747
Gene symbol: Socs3
Gene name: suppressor of cytokine signaling 3
Antibody: Anti-Socs3
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 1E: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: liver Present Regionally restricted 1E Expression was high on Ly76-positive fetal liver cells and was not expressed in Ly76-negative hepatocytes. There was great variation in the levels of expression in individual cells.

Specimen 1G: embryonic day 12.5; Socs3tm1Jni/Socs3tm1Jni (more )
Note: Double labeled: green - Socs3; red - Ly76 (assay MGI:5707760).
Structure Level Pattern Image Note
TS20: liver Absent 1G

Specimen 1H: embryonic day 9.5 (more )
Note: Double labeled: green - Socs3; red - Ly76 (assay MGI:5707760).
Structure Level Pattern Image Note
TS15: yolk sac blood vessel Absent 1H

Specimen 1I: embryonic day 12.5 (more )
Note: Double labeled: green - Socs3; red - Ly76 (assay MGI:5707760).
Structure Level Pattern Image Note
TS20: liver Present Regionally restricted 1I Expression was high on Ly76-positive fetal liver cells and was not expressed in Ly76-negative hepatocytes. There was great variation in the levels of expression in individual cells.

Specimen 1J: embryonic day 15.5 (more )
Note: Double labeled: green - Socs3; red - Ly76 (assay MGI:5707760).
Structure Level Pattern Image Note
TS23: liver sinusoid Absent 1J

Specimen 1K: embryonic day 12.5; Jak2tm1Jni/Jak2tm1Jni (more )
Note: Double labeled: green - Socs3; red - Ly76 (assay MGI:5707760).
Structure Level Pattern Image Note
TS20: liver Present Regionally restricted 1K Expression was observed in Ly76-positive fetal liver cells in the mutant.

Specimen 1L: embryonic day 12.5; Stat5btm1Jni/Stat5btm1Jni (more )
Note: Double labeled: green - Socs3; red - Ly76 (assay MGI:5707760).
Structure Level Pattern Image Note
TS20: liver Present Regionally restricted 1L Expression was observed in Ly76-positive fetal liver cells in the mutant.

Specimen 1M: embryonic day 12.5; Eportm1Jae/Eportm1Jae (more )
Note: Double labeled: green - Socs3; red - Ly76 (assay MGI:5707760).
Structure Level Pattern Image Note
TS20: liver Present Regionally restricted 1M Expression was observed in Ly76-positive fetal liver cells in the mutant.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
10/22/2024
MGI 6.24
The Jackson Laboratory