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Gene Expression Data
Assay Details
Assay
Reference: J:38619 Wilming LG, et al., The murine homologue of HIRA, a DiGeorge syndrome candidate gene, is expressed in embryonic structures affected in human CATCH22 patients. Hum Mol Genet. 1997 Feb;6(2):247-58
Assay type: RNA in situ
MGI Accession ID: MGI:5779876
Gene symbol: Hira
Gene name: histone cell cycle regulator
Probe: mA
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 6A: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: embryo Present Ubiquitous 6A
TS13: future brain neural fold Strong 6A Higher levels of expression in the cranial neural folds.
Specimen 6B: embryonic day 8.5 (more )
Structure Level Pattern Image Note
TS13: heart Present 6B
Specimen 6D: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: embryo Present Widespread 6D
TS15: 1st branchial arch Present 6D Enhanced expression in the first two branchial arches.
TS15: 2nd branchial arch Present 6D Enhanced expression in the first two branchial arches.
TS15: heart Absent 6D
Specimen not shown: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: branchial arch mesenchyme Present
Specimen 6E: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: limb bud Present 6E
TS17: fronto-nasal process Present 6E Expression in the frontonasal mass.
TS17: 1st branchial arch maxillary component Present 6E
TS17: 2nd branchial arch Present 6E Expression in the posterior part of arch 2.
TS17: head mesenchyme derived from neural crest Strong Regionally restricted 6E High level of expression in circumscribed spot just posterior to arches 1 and 2, corresponding to region where hindbrain neural crest cells (circumpharyngeal neural crest) reside prior to entering 3rd and 4th arches and developing gut.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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11/19/2024
MGI 6.24 		The Jackson Laboratory