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Gene Expression Data
Assay Details
Assay
Reference: J:169427 Kim HG, et al., WDR11, a WD protein that interacts with transcription factor EMX1, is mutated in idiopathic hypogonadotropic hypogonadism and Kallmann syndrome. Am J Hum Genet. 2010 Oct 8;87(4):465-79
Assay type: RNA in situ
MGI Accession ID: MGI:5817486
Gene symbol: Wdr11
Gene name: WD repeat domain 11
Probe: Wdr11 probe1
Probe preparation: Antisense labelled with dinitrophenyl RNA
Results
Specimen 6A: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: brain Strong Widespread 6A
Specimen 6B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: brain Present Widespread 6B Expression in the entire developing central nervous system, except for the spinal cord.
TS19: diencephalon Strong Regionally restricted 6B Strong expression in the neuroepithelium, including the diencephalic region that gives rise to hypothalamic neurons.
Specimen 6C: embryonic day 12.5 (more )
Structure Level Pattern Image Note
TS20: brain Present Widespread 6C Expression in the entire developing central nervous system, except for the spinal cord.
TS20: hypothalamus Strong Regionally restricted 6C Strong expression in the neuroepithelium, including the diencephalic region that gives rise to hypothalamic neurons.
TS20: limb Strong 6C Prominent expression in limbs at E12.5 and E13.5.
Specimen not shown E13.5: embryonic day 13.5 (more )
Structure Level Pattern Image Note
TS21: limb Strong Prominent expression in limbs at E12.5 and E13.5.
Specimen 6D: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cerebral cortex Strong 6D Highest levels of expression in developing cortex and olfactory bulb.
TS22: main olfactory bulb Strong 6D Highest levels of expression in developing cortex and olfactory bulb.
Specimen 6E: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: cerebral cortex Strong 6E Highest levels of expression in developing cortex and olfactory bulb.
TS22: main olfactory bulb Strong 6E Highest levels of expression in developing cortex and olfactory bulb.
Specimen 6H: postnatal adult (more )
Note: For hybridization of sections, Wdr11 probe2 (MGI:5817485) may have been used.
Structure Level Pattern Image Note
TS28: hypothalamic nucleus Strong Regionally restricted 6H Expression in single cells as well as clusters of neurons within hypothalamic nuclei.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/17/2024
MGI 6.24 		The Jackson Laboratory