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Phenotypes associated with Sphk1tm1Npa/Sphk1tm1Npa
Summary 1 genotype
Jump to Allelic Composition Genetic Background Genotype ID
hm1
 		Sphk1tm1Npa/Sphk1tm1Npa BALB/c-Sphk1tm1Npa MGI:3769495

Comparison Matrix Gene Expression + Phenotype


Genotype
MGI:3769495
hm1
Allelic
Composition		 Sphk1tm1Npa/Sphk1tm1Npa
Genetic
Background		 BALB/c-Sphk1tm1Npa
Find Mice Using the International Mouse Strain Resource (IMSR)
Mouse lines carrying:
Sphk1tm1Npa mutation (0 available); any Sphk1 mutation (29 available)
♀ phenotype observed in females
♂ phenotype observed in males
N normal phenotype
immune system
increased B cell number ( J:129314 )
• when treated with 1mg/kg FTY720, mice exhibit a 75% reduction in peripheral lymphocytes compared to wild-type mice

hematopoietic system
increased B cell number ( J:129314 )
• when treated with 1mg/kg FTY720, mice exhibit a 75% reduction in peripheral lymphocytes compared to wild-type mice


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory