The Phenotypes, Alleles & Disease Models project in MGI enables comparative phenotype analysis, searches for human disease models, and hypothesis generation by providing access to spontaneous, induced, and genetically engineered mutations and their strain-specific phenotypes.
This track data is updated weekly every Monday
QTL are quantitative trait loci, defined by the association of phenotypic characteristics with chromosomal regions. Generally many such loci contribute to quantitative characters, such as body metrics (e.g., length, adiposity), substance preference/aversion (e.g., to alcohol, cocaine), autoimmunity and susceptibility to infection, etc. Recently some QTL have been identified with their underlying genes. MGI captures information on strain-specific QTL variants, including genome location, descriptions of mapping analysis and significance scores, and descriptions of phenotypes using Mammalian Phenotype Ontology terms. QTL can be searched in the same way as other phenotypic alleles.
All data and analysis is provided by MGI. This information is also available on informatics.jax.org or for a complete data download please see http://www.informatics.jax.org/downloads/reports/index.html.
Hub data is maintained by Paul Hale (Paul.Hale@jax.org). Please email with any questions over this hub or the data herein.