MGI MouseCyc experimental GO annotations for PWY3DJ-35583: biosynthesis of prostaglandins

  • Gray arrows indicate "is_a"; Blue arrows indicate "part_of"; Black arrows indicate "regulates"; Green arrows indicate "positively_regulates"; Red arrows indicate "negatively_regulates"
    Graph is also available as SVG (requires plug-in)
    CategoryIDTermMouse gene EvidenceColor Key
    Molecular FunctionGO:001640415-hydroxyprostaglandin dehydrogenase (NAD+) activity Hpgd MGI_noIEAcolor key
    Molecular FunctionGO:001640415-hydroxyprostaglandin dehydrogenase (NAD+) activity Hpgd_RXN EC-NUMBERcolor key
    Molecular FunctionGO:00470423-alpha-hydroxysteroid dehydrogenase (B-specific) activity Hpgd_RXN AUTOMATED-NAME-MATCHcolor key
    Molecular FunctionGO:0003677DNA binding Ptges2 MGI_noIEAcolor key
    Molecular FunctionGO:0004303estradiol 17-beta-dehydrogenase activity Akr1c6 MGI_noIEAcolor key
    Molecular FunctionGO:0004364glutathione transferase activity Ptgds2 MGI_noIEAcolor key
    Molecular FunctionGO:0003674molecular_function Ptges3 MGI_noIEAcolor key
    Molecular FunctionGO:0004667prostaglandin-D synthase activity Ptgds2 MGI_noIEAcolor key
    Molecular FunctionGO:0004667prostaglandin-D synthase activity Ptges MGI_noIEAcolor key
    Molecular FunctionGO:0004667prostaglandin-D synthase activity Hpgd_RXN AUTOMATED-NAME-MATCHcolor key
    Molecular FunctionGO:0004667prostaglandin-D synthase activity Ptgds_RXN MANUALcolor key
    Molecular FunctionGO:0004667prostaglandin-D synthase activity Ptgds2_RXN AUTOMATED-NAME-MATCHcolor key
    Molecular FunctionGO:0050220prostaglandin-E synthase activity Ptges_RXN EC-NUMBERcolor key
    Molecular FunctionGO:0050220prostaglandin-E synthase activity Ptges2_RXN EC-NUMBERcolor key
    Molecular FunctionGO:0050220prostaglandin-E synthase activity Ptges3_RXN EC-NUMBERcolor key
    Molecular FunctionGO:0004666prostaglandin-endoperoxide synthase activity Ptgs1_RXN EC-NUMBERcolor key
    Molecular FunctionGO:0004666prostaglandin-endoperoxide synthase activity Ptgs2_RXN EC-NUMBERcolor key
    Molecular FunctionGO:0008116prostaglandin-I synthase activity Ptgis_RXN EC-NUMBERcolor key
    Molecular FunctionGO:0004796thromboxane-A synthase activity Tbxas1 MGI_noIEAcolor key
    Molecular FunctionGO:0004796thromboxane-A synthase activity Tbxas1_RXN EC-NUMBERcolor key
    Molecular FunctionGO:0016563transcription activator activity Ptges2 MGI_noIEAcolor key
    Biological ProcessGO:0042640anagen Ptgs2 MGI_noIEAcolor key
    Biological ProcessGO:0008150biological_process Ptges3 MGI_noIEAcolor key
    Biological ProcessGO:0030282bone mineralization Ptgs2 MGI_noIEAcolor key
    Biological ProcessGO:0030216keratinocyte differentiation Ptgs1 MGI_noIEAcolor key
    Biological ProcessGO:0030216keratinocyte differentiation Ptgs2 MGI_noIEAcolor key
    Biological ProcessGO:0008285negative regulation of cell proliferation Ptges MGI_noIEAcolor key
    Biological ProcessGO:0001516prostaglandin biosynthetic process Ptgs1 MGI_noIEAcolor key
    Biological ProcessGO:0006693prostaglandin metabolic process Ptgds2 MGI_noIEAcolor key
    Biological ProcessGO:0006693prostaglandin metabolic process Ptges MGI_noIEAcolor key
    Biological ProcessGO:0006693prostaglandin metabolic process Ptgs1 MGI_noIEAcolor key
    Biological ProcessGO:0008217regulation of blood pressure Ptgs1 MGI_noIEAcolor key
    Biological ProcessGO:0008217regulation of blood pressure Ptgs2 MGI_noIEAcolor key
    Biological ProcessGO:0042127regulation of cell proliferation Ptgs1 MGI_noIEAcolor key
    Biological ProcessGO:0042127regulation of cell proliferation Ptgs2 MGI_noIEAcolor key
    Biological ProcessGO:0045187regulation of circadian sleep/wake cycle, sleep Ptgds MGI_noIEAcolor key
    Biological ProcessGO:0045449regulation of transcription Ptges2 MGI_noIEAcolor key
    Biological ProcessGO:0046903secretion Ptges2 MGI_noIEAcolor key
    Biological ProcessGO:0008202steroid metabolic process Akr1c6 MGI_noIEAcolor key