This mutation was derived from the parent line <a href="http://www.informatics.jax.org/accession/MGI:5311366">b2b370Clo</a>.  <br><br>
<b>Summative Diagnosis:</b> 
<br> Cardiovascular defects: Supravalvular aortic stenosis (narrowed ascending aorta), Thickened great artery walls, Biventricular hypertrophy, and Pulmonary artery branch stenosis. <br>Non-cardiac defects: diaphragmatic hernia 

<br><br> <b>Fyler Codes</b>
<br>The Fyler code developed by The Boston Children's Heart Foundation in Boston Children's Hospital provides a hierarchical clinical diagnosis of congenital cardiovascular defects and other disorders. These codes are used to delineate pathology in the mutant mouse models that parallel human disease and can be cross referenced to the International Pediatric and Congenital Cardiac Code (IPCCC) (<A HREF="http://www.ipccc.net/">http://www.ipccc.net/</A>).
<table>
<br><br>
<table border="1">
  <tr> 
    <th>Fyler Code ID</th> 
    <th>Code Description</th> 
  </tr> 
<tr> 
    <td>1430</td> 
    <td>Aortic stenosis - supravalvar</td> 
  </tr> 
<tr> 
    <td>1617</td> 
    <td>Pulmonary stenosis, bilateral branch pulmonary artery</td> 
  </tr>
<tr> 
    <td>2600</td> 
    <td>Systemic artery anomaly</td> 
  </tr>
<tr> 
    <td>2700</td> 
    <td>Abnormal aortic arch</td> 
  </tr>

<tr> 
    <td>3608</td> 
    <td>Left ventricular hypertrophy</td> 
  </tr>
<tr> 
    <td>3609</td> 
    <td>Right ventricular hypertrophy</td> 
  </tr>
<tr> 
    <td>3804</td> 
    <td>Congenital heart disease</td> 
  </tr>
<tr> 
    <td>4031</td> 
    <td>Williams sydrome</td> 
  </tr>

<tr> 
    <td>4907</td> 
    <td>Non-cardiac thoracic abnormality</td> 
  </tr> 
</table><br>