Summative Diagnosis:
Heterotaxy including Situs inversus totalis
Cardiovascular Phenotype: Dextrocardia and and complex congenital heart defects associated with heterotaxy, including anomalous systemic venous return, atrioventricular septal defect (AVSD), right atrial isomerism (RAI), biventricular hypertrophy, and hypoplastic pulmonary artery. Also observed are mutants with situs inversus totatlis without congenital heart defects
Noncardiovascular Phenotype: Abnormal thoracic and abdominal organ situs anomalies, such as left lung isomerism, dextrogastria/levogastria, and dual inferior vena cava (IVC). A few mutants exhibited malaligned sternal vertebra, immotile airway cilia and craniofacial anomalies including micrognathia, cleft palate, duplex kidneys, and short snout

Fyler Codes
The Fyler code developed by The Boston Children's Heart Foundation in Boston Children's Hospital provides a hierarchical clinical diagnosis of congenital cardiovascular defects and other disorders. These codes are used to delineate pathology in the mutant mouse models that parallel human disease and can be cross referenced to the International Pediatric and Congenital Cardiac Code (IPCCC) (http://www.ipccc.net/).

Fyler Code ID	Code Description
0100	Situs inversus totalis
0110	Dextrocardia
0190	Heterotaxy syndrome
1100	Atrioventricular canal (endocardial cushion defect)
2810	Inferior vena cava anomaly
2966	Hypoplastic main pulmonary artery
3608	Left ventricular hypertrophy
3609	Right ventricular hypertrophy
3817	Abdominal situs ambiguous (abdominal heterotaxy)
3974	{I,L,I}
3988	{A,L,L}
4100	Skeletal, skin, muscle anomaly
4163	Micrognathia
4200	Respiratory anomaly
4239	Left bronchial isomerism
4851	Kartagener syndrome (siewart syndrome)(primary ciliary dyskinesia)
4876	Cleft palate
4906	Non-cardiac abnormality
4907	Non-cardiac thoracic abnormality
7505	Biventricular hypertrophy