Glossary:Gain-of-function Mutation

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Glossary Term

Glossary Term	Gain-of-function Mutation MGI Glossary
Definition	A type of mutation in which the altered gene product possesses a new molecular function or a new pattern of gene expression. Gain-of-function mutations are almost always Dominant or Semidominant. See also: Amorphic Mutation Antimorphic Mutation Hypermorphic Mutation Hypomorphic Mutation Loss-of-function Mutation Neomorphic Mutation Null Mutation

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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