Automated description from the Alliance of Genome Resources (Release 7.4.0)
Enables G protein-coupled receptor activity; G-protein alpha-subunit binding activity; and G-protein beta-subunit binding activity. Involved in several processes, including modulation of chemical synaptic transmission; negative regulation of renin secretion into blood stream; and positive regulation of intracellular signal transduction. Acts upstream of or within several processes, including dendritic cell homeostasis; regulation of interleukin-1 beta production; and thrombin-activated receptor signaling pathway. Predicted to be located in several cellular components, including endosome; platelet dense tubular network; and postsynaptic membrane. Predicted to be active in plasma membrane. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; heart; and lung. Orthologous to human F2R (coagulation factor II thrombin receptor).
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