Automated description from the Alliance of Genome Resources (Release 7.2.0)
Predicted to enable fibronectin binding activity; integrin binding activity; and syndecan binding activity. Involved in morphogenesis of an epithelium and regulation of inflammatory response. Acts upstream of or within several processes, including neuromuscular junction development; peripheral nervous system axon regeneration; and prostate gland development. Located in basement membrane; extracellular region; and interstitial matrix. Part of tenascin complex. Is active in perisynaptic extracellular matrix. Is expressed in several structures, including alimentary system; brain; genitourinary system; immune system; and skeletal system. Human ortholog(s) of this gene implicated in allergic conjunctivitis; asthma; autosomal dominant nonsyndromic deafness 56; and pulmonary hypertension. Orthologous to human TNC (tenascin C).
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