Automated description from the Alliance of Genome Resources (Release 7.2.0)
Enables several functions, including SMAD binding activity; nucleic acid binding activity; and transcription regulator inhibitor activity. Involved in dendritic transport of messenger ribonucleoprotein complex and negative regulation of DNA-templated transcription. Acts upstream of or within several processes, including epithelial cell proliferation; lymphocyte proliferation; and positive regulation of cell population proliferation. Located in dendrite cytoplasm; neuronal cell body; and nucleus. Is active in glutamatergic synapse and postsynapse. Is expressed in several structures, including alimentary system; eye; genitourinary system; heart; and nervous system. Human ortholog(s) of this gene implicated in autosomal dominant intellectual developmental disorder 31. Orthologous to human PURA (purine rich element binding protein A).
This site uses cookies.
Some cookies are essential for site operations and others help us analyze use and utility of our web site.
Please refer to our
privacy policy
for more information.