Automated description from the Alliance of Genome Resources (Release 7.4.0)
Enables arachidonate 14,15-epoxygenase activity. Involved in arachidonate metabolic process. Predicted to be located in plasma membrane. Predicted to be active in cytoplasm and intracellular membrane-bounded organelle. Is expressed in several structures, including genitourinary system; liver; lung; nervous system; and spleen. Human ortholog(s) of this gene implicated in several diseases, including Plasmodium falciparum malaria; carcinoma (multiple); end stage renal disease; glucose metabolism disease (multiple); and hypertension (multiple). Orthologous to several human genes including CYP2C18 (cytochrome P450 family 2 subfamily C member 18); CYP2C19 (cytochrome P450 family 2 subfamily C member 19); and CYP2C9 (cytochrome P450 family 2 subfamily C member 9).
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