Automated description from the Alliance of Genome Resources (Release 8.0.0)
Enables glutamate-cysteine ligase catalytic subunit binding activity. Acts upstream of or within several processes, including cellular response to leukemia inhibitory factor; glutathione biosynthetic process; and positive regulation of glutamate-cysteine ligase activity. Part of glutamate-cysteine ligase complex. Is expressed in several structures, including alimentary system; genitourinary system; liver; nervous system; and vibrissa. Human ortholog(s) of this gene implicated in myocardial infarction and vascular dementia. Orthologous to human GCLM (glutamate-cysteine ligase modifier subunit).
This site uses cookies.
Some cookies are essential for site operations and others help us analyze use and utility of our web site.
Please refer to our
privacy policy
for more information.