Automated description from the Alliance of Genome Resources (Release 7.2.0)
Enables plus-end-directed microtubule motor activity. Involved in anterograde axonal transport; neuromuscular synaptic transmission; and neuron-neuron synaptic transmission. Acts upstream of or within mitochondrion transport along microtubule. Located in cytoplasmic vesicle membrane and mitochondrion. Part of microtubule associated complex. Is active in postsynapse and presynapse. Is expressed in several structures, including alimentary system; brain; genitourinary system; hemolymphoid system; and skeletal musculature. Used to study Charcot-Marie-Tooth disease type 2A1. Human ortholog(s) of this gene implicated in Charcot-Marie-Tooth disease type 2A1; hepatocellular carcinoma; multiple sclerosis; neuroblastoma; and ovary epithelial cancer. Orthologous to human KIF1B (kinesin family member 1B).
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