Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables Wnt receptor activity. Involved in several processes, including axon guidance; positive regulation of neuroblast proliferation; and sympathetic ganglion development. Acts upstream of or within several processes, including inner ear morphogenesis; nervous system development; and post-anal tail morphogenesis. Located in several cellular components, including apical plasma membrane; filopodium tip; and lateral plasma membrane. Is active in glutamatergic synapse and presynaptic active zone membrane. Colocalizes with presynaptic active zone. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Used to study hydrocephalus. Human ortholog(s) of this gene implicated in Williams-Beuren syndrome and schizophrenia. Orthologous to human FZD3 (frizzled class receptor 3).

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Gene Ontology Evidence Code Abbreviations:

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