Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.5.0)

Enables G protein-coupled serotonin receptor activity; GTPase activator activity; and serotonin binding activity. Involved in several processes, including ERK1 and ERK2 cascade; phospholipase C-activating serotonin receptor signaling pathway; and positive regulation of endothelial cell proliferation. Acts upstream of or within heart development. Located in cytoplasm and plasma membrane. Part of G protein-coupled serotonin receptor complex. Is expressed in several structures, including alimentary system; central nervous system; embryo mesenchyme; genitourinary system; and sensory organ. Used to study hypertrophic cardiomyopathy. Human ortholog(s) of this gene implicated in metabolic dysfunction-associated steatohepatitis and steatotic liver disease. Orthologous to human HTR2B (5-hydroxytryptamine receptor 2B).

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Gene Ontology Evidence Code Abbreviations:

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