Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables BMP binding activity and BMP receptor activity. Involved in several processes, including BMP signaling pathway; circulatory system development; and negative regulation of cell proliferation involved in heart valve morphogenesis. Acts upstream of or within several processes, including limb development; maternal placenta development; and mesoderm formation. Located in cell surface and postsynaptic density. Is active in several cellular components, including cell body; clathrin-coated pit; and dendrite. Is expressed in several structures, including alimentary system; central nervous system; early conceptus; embryo ectoderm; and genitourinary system. Used to study primary pulmonary hypertension. Human ortholog(s) of this gene implicated in heart septal defect; primary pulmonary hypertension; pulmonary hypertension; and pulmonary venoocclusive disease 1. Orthologous to human BMPR2 (bone morphogenetic protein receptor type 2).

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Gene Ontology Evidence Code Abbreviations:

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