Automated description from the Alliance of Genome Resources (Release 7.2.0)
Predicted to enable calcium-dependent cysteine-type endopeptidase inhibitor activity and protease binding activity. Predicted to be involved in egg activation and negative regulation of type B pancreatic cell apoptotic process. Predicted to act upstream of or within protein catabolic process. Located in membrane. Is expressed in several structures, including alimentary system; gonad; immune system; lung; and nervous system. Human ortholog(s) of this gene implicated in PLACK syndrome; Parkinson's disease; autoimmune disease (multiple); congenital myasthenic syndrome 1A; and vasculitis. Orthologous to human CAST (calpastatin).
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