Automated description from the Alliance of Genome Resources (Release 7.2.0)
Enables 5-methylcytosine dioxygenase activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including dendrite morphogenesis; inner cell mass cell differentiation; and positive regulation of macromolecule biosynthetic process. Acts upstream of or within DNA demethylation and epigenetic programing of male pronucleus. Located in nucleus. Is expressed in several structures, including brain; early conceptus; immune system; lower urogenital tract; and reproductive system. Orthologous to human TET1 (tet methylcytosine dioxygenase 1).
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