Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Predicted to enable cysteine-type endopeptidase inhibitor activity involved in apoptotic process and ubiquitin protein ligase activity. Involved in several processes, including necroptotic process; negative regulation of necroptotic process; and negative regulation of reactive oxygen species metabolic process. Acts upstream of or within cellular response to tumor necrosis factor; positive regulation of protein polyubiquitination; and regulation of non-canonical NF-kappaB signal transduction. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of protein-containing complex. Predicted to be active in cytoplasm and nucleus. Is expressed in central nervous system and genitourinary system. Human ortholog(s) of this gene implicated in colorectal carcinoma; esophagus adenocarcinoma; extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue; hepatocellular carcinoma; and lung non-small cell carcinoma. Orthologous to human BIRC3 (baculoviral IAP repeat containing 3).

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Gene Ontology Evidence Code Abbreviations:

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