Automated description from the Alliance of Genome Resources (Release 7.3.0)
Enables protein homodimerization activity; protein serine/threonine kinase activator activity; and protein serine/threonine kinase activity. Involved in JNK cascade and post-translational protein modification. Acts upstream of or within negative regulation of motor neuron apoptotic process. Located in cytosol; growth cone; and plasma membrane. Is expressed in several structures, including alimentary system; genitourinary system; integumental system; nervous system; and sensory organ. Orthologous to human MAP3K12 (mitogen-activated protein kinase kinase kinase 12).
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