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Gene Ontology Classifications
Symbol
Name
ID
Hsf4
heat shock transcription factor 4
MGI:1347058

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Predicted to enable several functions, including RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; identical protein binding activity; and protein phosphatase binding activity. Predicted to be involved in lens fiber cell differentiation and negative regulation of transcription by RNA polymerase II. Predicted to be located in chromatin and nuclear speck. Predicted to be active in nucleus. Is expressed in several structures, including brain; lens; respiratory system; submandibular gland; and urinary system. Used to study cataract 5 multiple types. Human ortholog(s) of this gene implicated in cataract and cataract 5 multiple types. Orthologous to human HSF4 (heat shock transcription factor 4).



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Gene Ontology Evidence Code Abbreviations:

Experimental:
EXP
Inferred from experiment
HMP
Inferred from high throughput mutant phenotype
HGI
Inferred from high throughput genetic interaction
HDA
Inferred from high throughput direct assay
HEP
Inferred from high throughput expression pattern
IDA
Inferred from direct assay
IEP
Inferred from expression pattern
IGI
Inferred from genetic interaction
IMP
Inferred from mutant phenotype
IPI
Inferred from physical interaction
Homology:
IAS
Inferred from ancestral sequence
IBA
Inferred from biological aspect of ancestor
IBD
Inferred from biological aspect of descendant
IKR
Inferred from key residues
IMR
Inferred from missing residues
IRD
Inferred from rapid divergence
ISA
Inferred from sequence alignment
ISM
Inferred from sequence model
ISO
Inferred from sequence orthology
ISS
Inferred from sequence or structural similarity
Automated:
IEA
Inferred from electronic annotation
RCA
Reviewed computational analysis
Other:
IC
Inferred by curator
NAS
Non-traceable author statement
ND
No biological data available
TAS
Traceable author statement

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Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
11/19/2024
MGI 6.24
The Jackson Laboratory