Automated description from the Alliance of Genome Resources (Release 7.5.0)
Enables ornithine decarboxylase activator activity. Involved in positive regulation of polyamine transmembrane transport. Located in nucleus. Is expressed in embryo; extraembryonic component; pancreas epithelium; and placenta. Human ortholog(s) of this gene implicated in esophagus squamous cell carcinoma; hepatocellular carcinoma; and liver cirrhosis. Orthologous to human AZIN1 (antizyme inhibitor 1).
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