Automated description from the Alliance of Genome Resources (Release 7.3.0)
Enables DNA-directed DNA polymerase activity. Acts upstream of or within cellular response to UV-C; postreplication repair; and pyrimidine dimer repair. Predicted to be located in cytosol and nucleoplasm. Predicted to be active in nucleus; replication fork; and site of double-strand break. Is expressed in several structures, including genitourinary system; heart; hemolymphoid system gland; liver; and lung. Used to study xeroderma pigmentosum variant type. Human ortholog(s) of this gene implicated in female breast cancer and xeroderma pigmentosum variant type. Orthologous to human POLH (DNA polymerase eta).
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