Automated description from the Alliance of Genome Resources (Release 7.3.0)
Predicted to enable succinate dehydrogenase (quinone) activity. Predicted to be involved in aerobic respiration; respiratory electron transport chain; and succinate metabolic process. Located in mitochondrion. Part of respiratory chain complex II (succinate dehydrogenase). Is expressed in several structures, including alimentary system; brain; genitourinary system; respiratory system; and sensory organ. Used to study type 2 diabetes mellitus. Human ortholog(s) of this gene implicated in Carney-Stratakis syndrome; gastrointestinal stromal tumor; mitochondrial complex II deficiency; paraganglioma; and pheochromocytoma. Orthologous to human SDHB (succinate dehydrogenase complex iron sulfur subunit B).
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