Automated description from the Alliance of Genome Resources (Release 7.4.0)
Predicted to enable WW domain binding activity. Acts upstream of or within intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator. Located in endoplasmic reticulum and nuclear envelope. Is expressed in blood vessel; cortical plate; extraembryonic component; foregut diverticulum; and meninges. Orthologous to human SHISA5 (shisa family member 5).
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