Automated description from the Alliance of Genome Resources (Release 7.4.0)
Predicted to enable enzyme binding activity; poly-ADP-D-ribose binding activity; and ubiquitin-protein transferase activity. Predicted to be involved in several processes, including cellular response to hydrogen peroxide; positive regulation of canonical Wnt signaling pathway; and protein ubiquitination. Predicted to be located in cytosol; nucleoplasm; and plasma membrane. Predicted to be active in cytoplasm and nucleus. Is expressed in central nervous system and genitourinary system. Used to study osteochondrodysplasia. Orthologous to human RNF146 (ring finger protein 146).
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