Automated description from the Alliance of Genome Resources (Release 7.4.0)
Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein polyubiquitination; retrograde protein transport, ER to cytosol; and ubiquitin-dependent protein catabolic process. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum. Is expressed in several structures, including brain; cardiovascular system; genitourinary system; gut; and hemolymphoid system gland. Orthologous to human TMEM129 (transmembrane protein 129, E3 ubiquitin ligase).
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