Automated description from the Alliance of Genome Resources (Release 7.4.0)
Predicted to enable AMP binding activity. Involved in flagellated sperm motility. Acts upstream of or within cerebrospinal fluid circulation; epithelial cilium movement involved in determination of left/right asymmetry; and regulation of cilium beat frequency involved in ciliary motility. Located in 9+0 motile cilium. Is active in axonemal B tubule inner sheath and sperm flagellum. Is expressed in lateral ventricle choroid plexus; lung; metencephalon part of 4th ventricle choroid plexus; and olfactory epithelium. Human ortholog(s) of this gene implicated in visceral heterotaxy. Orthologous to human CFAP45 (cilia and flagella associated protein 45).
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