Automated description from the Alliance of Genome Resources (Release 7.5.0)
Enables ubiquitin protein ligase activity. Involved in antigen processing and presentation of peptide antigen via MHC class II; immune response; and protein polyubiquitination. Located in bounding membrane of organelle; endoplasmic reticulum membrane; and trans-Golgi network membrane. Is expressed in brain; glossopharyngeal ganglion; and spinal cord. Orthologous to human MARCHF1 (membrane associated ring-CH-type finger 1).
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