Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables ubiquitin protein ligase activity. Acts upstream of or within several processes, including adult walking behavior; protein K48-linked ubiquitination; and toll-like receptor 3 signaling pathway. Predicted to be active in endoplasmic reticulum membrane. Used to study hereditary ataxia. Human ortholog(s) of this gene implicated in autosomal dominant sensory ataxia 1 and hereditary spastic paraplegia 85. Orthologous to human RNF170 (ring finger protein 170).

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Gene Ontology Evidence Code Abbreviations:

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