Automated description from the Alliance of Genome Resources (Release 7.4.0)
Predicted to enable several functions, including GABA receptor binding activity; guanyl-nucleotide exchange factor activity; and protein kinase A regulatory subunit binding activity. Predicted to be involved in several processes, including Golgi to plasma membrane transport; endosome organization; and positive regulation of tumor necrosis factor production. Predicted to act upstream of or within intracellular signal transduction. Predicted to be located in several cellular components, including Golgi apparatus; microtubule cytoskeleton; and recycling endosome. Predicted to be active in several cellular components, including GABA-ergic synapse; glutamatergic synapse; and postsynapse. Is expressed in brown fat; central nervous system; duodenum; thymus; and trunk. Human ortholog(s) of this gene implicated in periventricular nodular heterotopia. Orthologous to human ARFGEF2 (ADP ribosylation factor guanine nucleotide exchange factor 2).
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