Automated description from the Alliance of Genome Resources (Release 7.4.0)
Enables chromatin-protein adaptor activity; lysine-acetylated histone binding activity; and nucleic acid binding activity. Involved in DNA methylation-dependent heterochromatin formation; negative regulation of transcription by RNA polymerase I; and rDNA heterochromatin formation. Acts upstream of or within chromatin remodeling. Located in nucleolus and rDNA heterochromatin. Part of NoRC complex and chromatin silencing complex. Is expressed in several structures, including central nervous system; early conceptus; eye; genitourinary system; and paraxial mesenchyme. Orthologous to human BAZ2A (bromodomain adjacent to zinc finger domain 2A).
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