Automated description from the Alliance of Genome Resources (Release 7.3.0)
Predicted to enable 3-oxo-5-beta-steroid 4-dehydrogenase activity; aldose reductase (NADPH) activity; and ketosteroid monooxygenase activity. Predicted to be involved in several processes, including C21-steroid hormone metabolic process; androgen metabolic process; and cholesterol catabolic process. Predicted to act upstream of or within bile acid biosynthetic process. Predicted to be located in cytoplasm. Predicted to be active in cytosol. Is expressed in several structures, including alimentary system; genitourinary system; heart; hemolymphoid system gland; and nervous system. Human ortholog(s) of this gene implicated in congenital bile acid synthesis defect 2. Orthologous to human AKR1D1 (aldo-keto reductase family 1 member D1).
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