Automated description from the Alliance of Genome Resources (Release 7.4.0)
Enables actin filament binding activity and identical protein binding activity. Involved in several processes, including cellular response to fluid shear stress; glomerulus morphogenesis; and renal tubule development. Acts upstream of or within several processes, including actin filament polymerization; adherens junction maintenance; and positive regulation of actin filament bundle assembly. Located in adherens junction and cytoplasm. Is expressed in several structures, including central nervous system; metanephros; myotome; sensory organ; and spleen. Used to study non-Hodgkin lymphoma. Orthologous to human MTSS1 (MTSS I-BAR domain containing 1).
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