Automated description from the Alliance of Genome Resources (Release 7.2.0)
Predicted to enable several functions, including disordered domain specific binding activity; dynein complex binding activity; and microtubule binding activity. Involved in several processes, including establishment of mitotic spindle orientation; positive regulation of BMP signaling pathway; and positive regulation of keratinocyte differentiation. Acts upstream of or within lung epithelial cell differentiation. Located in several cellular components, including lateral cell cortex; mitotic spindle pole; and nuclear matrix. Is expressed in several structures, including 1st branchial arch mandibular component; early embryo; facial prominence; oocyte; and telencephalon. Human ortholog(s) of this gene implicated in acute promyelocytic leukemia. Orthologous to human NUMA1 (nuclear mitotic apparatus protein 1).
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