Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables several functions, including chondroitin sulfate binding activity; heparan sulfate proteoglycan binding activity; and transmembrane transporter binding activity. Involved in several processes, including negative regulation of sodium ion transmembrane transport; positive regulation of Rac protein signal transduction; and positive regulation of protein modification process. Acts upstream of or within several processes, including positive regulation of motor neuron apoptotic process; positive regulation of transcription by RNA polymerase II; and regulation of synaptic activity. Located in basement membrane; cell surface; and sarcolemma. Is active in extracellular space and synapse. Is expressed in several structures, including epithelium; lower jaw; musculature; nervous system; and retina. Used to study congenital myasthenic syndrome 8. Human ortholog(s) of this gene implicated in congenital myasthenic syndrome 8. Orthologous to human AGRN (agrin).

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Gene Ontology Evidence Code Abbreviations:

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