Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.5.0)

Enables receptor ligand activity; type 1 angiotensin receptor binding activity; and type 2 angiotensin receptor binding activity. Involved in several processes, including G protein-coupled receptor signaling pathway; aldosterone secretion; and angiotensin-mediated vasodilation involved in regulation of systemic arterial blood pressure. Acts upstream of or within several processes, including positive regulation of intracellular signal transduction; positive regulation of metabolic process; and regulation of systemic arterial blood pressure by renin-angiotensin. Located in extracellular space. Is active in extracellular region. Is expressed in several structures, including axial skeleton; central nervous system; foregut mesenchyme; genitourinary system; and liver. Human ortholog(s) of this gene implicated in several diseases, including Fabry disease; Henoch-Schoenlein purpura; artery disease (multiple); heart conduction disease (multiple); and hydronephrosis. Orthologous to human AGT (angiotensinogen).

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Gene Ontology Evidence Code Abbreviations:

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