Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables several functions, including ATPase binding activity; potassium channel regulator activity; and transmembrane transporter binding activity. Involved in several processes, including positive regulation of ion transmembrane transporter activity; regulation of cardiac muscle cell action potential; and regulation of heart contraction. Acts upstream of or within cardiac muscle contraction; regulation of cardiac muscle cell membrane potential; and regulation of cation channel activity. Located in several cellular components, including T-tubule; intercalated disc; and myofibril. Is active in paranodal junction. Is extrinsic component of cytoplasmic side of plasma membrane. Is expressed in central nervous system; eye; genitourinary system; and heart. Used to study ankyrin-B-related cardiac arrhythmia; autistic disorder; and sinoatrial node disease. Human ortholog(s) of this gene implicated in ankyrin-B-related cardiac arrhythmia; atrial fibrillation; long QT syndrome; and sick sinus syndrome. Orthologous to human ANK2 (ankyrin 2).

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Gene Ontology Evidence Code Abbreviations:

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