Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.5.0)

Enables several functions, including ferrochelatase activity; heme binding activity; and iron-responsive element binding activity. Involved in heme A biosynthetic process; heme B biosynthetic process; and heme O biosynthetic process. Acts upstream of or within several processes, including multicellular organismal-level iron ion homeostasis; regulation of protein metabolic process; and very-low-density lipoprotein particle assembly. Located in mitochondrial inner membrane. Is active in mitochondrial matrix. Is expressed in several structures, including choroid plexus; heart; integumental system; liver and biliary system; and respiratory system. Used to study erythropoietic protoporphyria. Human ortholog(s) of this gene implicated in cutaneous porphyria and erythropoietic protoporphyria. Orthologous to human FECH (ferrochelatase).

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Gene Ontology Evidence Code Abbreviations:

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