Automated description from the Alliance of Genome Resources (Release 7.5.0)
Enables heparin binding activity; protein homodimerization activity; and signaling receptor binding activity. Involved in several processes, including myoblast migration involved in skeletal muscle regeneration; negative regulation of skeletal muscle tissue growth; and positive regulation of lamellipodium assembly. Acts upstream of or within cellular response to dexamethasone stimulus and transforming growth factor beta receptor signaling pathway. Located in extracellular space. Is expressed in several structures, including abdominal wall; choroid plexus; connective tissue; embryo mesenchyme; and skeletal musculature. Used to study myostatin-related muscle hypertrophy. Human ortholog(s) of this gene implicated in myostatin-related muscle hypertrophy. Orthologous to human MSTN (myostatin).
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