Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables G protein activity and adenylate cyclase activator activity. Involved in several processes, including cellular response to glucagon stimulus; positive regulation of cold-induced thermogenesis; and positive regulation of insulin secretion. Acts upstream of or within several processes, including adenylate cyclase-activating dopamine receptor signaling pathway; positive regulation of cell differentiation; and skeletal system development. Located in dendrite and membrane. Is active in plasma membrane. Is expressed in several structures, including cardiovascular system; central nervous system; early conceptus; gonad; and somite. Used to study Albright's hereditary osteodystrophy; pseudohypoparathyroidism; pseudopseudohypoparathyroidism; and schizophrenia. Human ortholog(s) of this gene implicated in several diseases, including ACTH-independent macronodular adrenal hyperplasia 1; obesity; pituitary adenoma 3; progressive osseous heteroplasia; and pseudohypoparathyroidism (multiple). Orthologous to human GNAS (GNAS complex locus).

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Gene Ontology Evidence Code Abbreviations:

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