Go Annotations as Summary Text (Tabular View) (GO Graph)

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Automated description from the Alliance of Genome Resources (Release 7.4.0)

Enables insulin-like growth factor binding activity and insulin-like growth factor receptor activity. Involved in several processes, including adrenal gland development; insulin-like growth factor receptor signaling pathway; and positive regulation of cold-induced thermogenesis. Acts upstream of or within several processes, including exocrine pancreas development; peptidyl-tyrosine autophosphorylation; and regulation of intracellular signal transduction. Located in T-tubule. Is active in glutamatergic synapse. Is expressed in several structures, including alimentary system; brain; genitourinary system; limb; and lung. Human ortholog(s) of this gene implicated in several diseases, including IgA glomerulonephritis; dementia (multiple); kidney cancer (multiple); liver disease (multiple); and neurodegenerative disease (multiple). Orthologous to human IGF1R (insulin like growth factor 1 receptor).

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Gene Ontology Evidence Code Abbreviations:

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