Automated description from the Alliance of Genome Resources (Release 7.3.0)
Predicted to enable hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides and serine-type endopeptidase activity. Predicted to be involved in regulation of systemic arterial blood pressure and zymogen activation. Predicted to be located in several cellular components, including acrosomal vesicle; apical part of cell; and extracellular space. Predicted to be part of protein-containing complex. Predicted to be active in secretory granule. Is expressed in early conceptus; embryo; salivary gland; testis; and ureter. Human ortholog(s) of this gene implicated in cardiomyopathy; chronic kidney disease; end stage renal disease; hypertension; and myocardial infarction. Orthologous to several human genes including KLK1 (kallikrein 1).
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