Automated description from the Alliance of Genome Resources (Release 7.4.0)
Predicted to enable 2'-5'-oligoadenylate synthetase activity and double-stranded RNA binding activity. Predicted to be involved in several processes, including cellular response to cytokine stimulus; regulation of cytokine production; and regulation of innate immune response. Predicted to be located in mitochondrion; nucleus; and ribosome. Predicted to be active in cytosol; membrane; and nucleoplasm. Predicted to colocalize with cytoplasm. Is expressed in several structures, including esophagus; intestine; liver; male reproductive gland or organ; and spleen. Human ortholog(s) of this gene implicated in primary immunodeficiency disease. Orthologous to human OAS1 (2'-5'-oligoadenylate synthetase 1).
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